Twenty people were hospitalized and two were killed after a powerful storm moved through East Tennessee late Tuesday night into early Wednesday morning.

A meteorologist from the National Weather Service toured the damage Wednesday and confirmed that a tornado had touched down in McMinn County. They have yet to determine its strength.

EMS transported eight people to the hospital and 12 were taken by personal vehicles in McMinn County, officials said.

In nearby Polk County, an official confirmed two people have been killed in the severe weather that hit overnight. Tennessee Emergency Management Agency spokesman Dean Flener says a husband and wife died and two others were injured in Polk County.

McMinn County Schools are also among the East Tennessee school districts closed Wednesday.

Multiple areas across East Tennessee saw storm damage overnight.

The 900 block of East 5th Avenue in Knoxville was closed Wednesday morning due to flooding, according to KPD.

The West Knoxville Glass Company in West Knoxville experienced extensive damage. Knoxville Fire Department spokesperson D.J. Corcoran said no one was injured in the collapse of the building. The building was empty and for sale.

Corcoran said weather was a factor in the collapse of the building around 3:20 a.m. Wednesday.

There are trees down and scattered damage throughout McMinn County. The Save-A-Lot in Athens suffered extensive damage from the storms.

Authorities confirm to 10News people were trapped in their homes due to downed power lines.

The McMinn County mayor is asking people to reduce cell phone use due to coverage issues.

The Red Cross is preparing a shelter at Keith Memorial United Methodist Church on 600 West Madison Ave. in Athens.

Photo Gallery: Storm damages parts of East Tennessee