After a tight first half, the Lady Vols poured it on and pulled away from Liberty in the 3rd quarter to win 100-60.
With Holly Warlick going deep in to her bench in the second half, the Lady Vols scored 38 points in the 3rd to take control of the game.
"A couple of things we wanted to focus on were great ball pressure, denying one pass away and keeping them off of the offensive boards," head coach Holly Warlick said.
"Offensively, we wanted to hit shots in the paint. I thought we checked off all of those things we wanted to focus on.
"I’m really proud of our young ladies. They played hard and we got a lot of people playing time. They did an outstanding job."
Tennessee scored in the triple digits for the 4th time this season and first time in an NCAA tournament game since 2006, while breaking the school record for field goal percentage in an NCAA Tournament game, shooting 61.7 percent.
Seven Lady Vols scored in double figures and Tennessee's bench contributed 39 points. Rennia Davis and Cheridene Green both recorded double-doubles.
Tennessee will play Oregon State in the second round on Sunday. Tip off is set for 2 p.m. at Thompson Boling Arena.
UPDATE: The Lady Vols are extending their lead over Liberty going into the final quarter.
Meme Jackson hit a 3-point shot at the buzzer to give the Lady Vols a 74-48 lead at the start of the fourth quarter.
UPDATE: The Lady Vols lead Liberty 36-28 going into the half.
Cheridene Green led the scoring for the Lady Vols in the first half with 10 points. Rennia Davis had 8, followed by Mercedes Russell with 5 and Jamie Nared with 4. The Lady Vols shot 43% from the floor with no 3-point baskets.
The Lady Vols begin the NCAA tournament on Rocky Top.
The team drew a No. 3 seed in the Lexington Region, and will host Liberty University on Friday at 2:30 p.m. at Thompson Boling Arena.
You can watch on ESPN2 or online here.
"I thought with our strength of schedule and what we did, I thought a three seed was good," head coach Holly Warlick said. "If we would have advanced more in the (SEC) tournament, maybe we would've gotten a better seed, but we lost a couple games that I think hurt us. I'm pleased with the three seed, absolutely."
The Lady Vols will host the first two rounds of the tournament. Tennessee has never lost an NCAA Tournament game in Knoxville, going 56-0, and is the only program to make it to all 37 NCAA Tournaments in women's basketball history.
"We made it to the Elite Eight my first two years here and then the round of 32," senior guard/forward Jaime Nared said. Any team in the country would be happy with that, but that's not the expectation here. It's to go to the Final Four and win a national championship, so give it you're all because we're only promised the game against Liberty."
If the Lady Vols get past Liberty, they'll take on the winner of the Oregon State-Western Kentucky game in the second round.
Tennessee has been a no. 3 seed three times previously, the last time was in 1997 when they won the national championship.