Update: 12:40 p.m.
Police identified the driver killed in the crash as Timothy Porcella, of Knoxville.
According to Sergeant Travis Brasfield, alcohol appears to be a factor. Porcella was not wearing a seatbelt when he crashed into a semi tractor and trailer.
Brasfield said the semi driver, Shawn Bardell of Columbia, Alabama, suffered minor injuries and was taken to University of Tennessee Medical Center.
Update: 9:53 a.m.
Dispatch said I-640W is back open after a fatal crash Saturday morning.
Westbound traffic was reopened, but the ramp at Broadway Avenue is expected to remain closed for several hours.
Update: 9:16 a.m.
The Knoxville Police Department said I-640W will remain closed between I-40 and I-75 until at least 2:00 p.m. Saturday.
A fatal crash early Saturday morning closed the interstate and the ramps at North Broadway to I-640W, I-40W to I-640W, and Washington Pike to I-640W.
Westbound drivers are encouraged to use I-40 to I-275 as a detour to reach I-75N.
Crews are still cleaning up the debris after a speeding car crashed into a semi-truck. The interstate was orginally expected to reopen by 8:00 a.m. Saturday.
(WBIR-Knoxville) A driver was killed early Saturday morning after crashing into a semi truck on 1-640.
The Knoxville Police Department said according to witness statements, the driver of an Infiniti G35 was traveling at a high rate of speed, lost control, and slammed into the side of a semi truck.
Police said on impact, the semi was knocked on its side, onto the ramp of I-640 from Broadway around 3:35 a.m. Saturday.
Officers said the driver of the Infiniti was ejected and pronounced dead at the scene. The driver and passenger of the semi truck were not injured.
The Knoxville Fire Department responded to the scene due to diesel fuel that leaked from the semi truck.
The interstate is expected to reopen by 8:00 a.m. but officers said the on-ramp would remain closed for an uknown amount of time.