Lenoir City hosts West in a District 4-AAA match-up on cable channel 10News2. Both schools come into the game with only one loss.
The Rebels fell to Maryville 47-33 in Week 2 while Lenoir City lost to Bearden 24-14 in Week 4.
The Panthers and Rebels have played every year since 2005, with West taking all seven of those games. West won last season 45-29.
Two of the biggest rivals in East Tennessee, Bearden and Farragut, will square off on Friday night.
Farragut has won six in a row in the series including a 31-14 victory last season. Bearden last beat the Admirals in the quarterfinals of the 2007 state playoffs.
Bearden won its first five games before falling to Maryville last week. The Bulldogs gave Maryville a fight though, holding the Rebels scoreless until their final possession of the second quarter.
Farragut comes in at 3-3 but its losses have all come against state ranked opponents- 6A #4 Dobyns-Bennett, 6A #9 Oak Ridge and 5A #2 West.
On Thursday night, two IMAC powerhouses Sevier County and Morristown West do battle.
Sevier County (5-1, 3-0) has beaten Morristown West (4-2, 2-1) in all three meetings since joining the IMAC in the 2009 realignment. In fact, the Smoky Bears have only lost one IMAC game; that came against Jefferson County in 2010.
Something has to give in the meeting between winless schools Austin-East and Union County.
The Roadrunners pounded Union County 66-0 last year but are struggling through a coaching change. The Patriots are in the middle of a 24-game losing streak with their last win coming against Carter in 2010.
For a list of this week's games from around the area, click here.
Several East Tennessee teams are ranked in state polls.
Here are the area teams ranked in the USA Today Super 25 Computer Poll:
20. Oak Ridge
24. Sevier County
The AP ranks the top ten schools in each playoff classification. Here are the East Tennessee teams that made the cut after Week 6:
9. Oak Ridge
4. Lenoir City
Others receiving votes: South-Doyle
3. Grace Christian