The Tennessee Lady Vols used a 22-2 run late in the first half to break open a close game and went on to rout Rice, 101-48.
Meighan Simmons tossed in 22 points to lead the way for Tennessee, while freshman Bashaara Graves had 18 points and Isabelle Harrison scored 16 points and had 12 rebounds.
Former Webb star Jessica Goswitz struggled in her return home, scoring 3 points for the Owls.
Here is more on the game from the University of Tennessee:
Tennessee rallied from an early six-point deficit to blow out Rice, 101-48, in the 2012-13 home opener before 10,913 at Thompson-Boling Arena.
Senior Meighan Simmons tallied 22 points as she shot 8-of-12 from the floor. It was her 12th-career game with 20-plus points with the Lady Vols (2-1).
Sophomore Isabelle Harrison scored a career-high 16 points and grabbed a career-high tying 12 rebounds for her second-career double-double.
Freshman Bashaara Graves scored in double-figures for the third time in three college games with 18.
Senior Kamiko Williams had her best-scoring game in two seasons with 12 points.
The game marked Tennessee's first 100-point game since a 110-45 win over Alabama on Jan. 6, 2011.
Tennessee outscored Rice 49-10 bridging the halves over a span of 16:36 to blow open the game and built a 30-point plus advantage.
After Rice had 22 points in the game's first 8:18. As Tennessee's defense buckled up, Rice was limited to 26 points for the remainder of the game, covering nearly 32 minutes.
Rice (1-1) was led by Jessica Kuster (16) and Megan Palmer (15).
Tennessee shot 57 percent from the floor for the game including 66 percent in the second half (23-of-35).
Tennessee outscored the Owls, 32-0, off turnovers and 20-0 on fastbreak points. The Lady Vols had just seven turnovers, including just one in the first half.
The second half featured lots of spurts.
Freshman Nia Moore scored her first-career points on a bucket during a 16-0 run that put UT up 93-41 with five minutes left.
An 8-0 run closed by a Williams 3-pointer with 10:28 left, gave the Lady Vols a 77-38 lead.
A 9-0 spurt put Tennessee ahead by 30 at 63-32 on a lay-up by Ariel Massengale.
Tennessee led 45-27 at halftime as the Lady Vols outscored Rice 29-5 to end the first half. Simmons punctuated the half with a bank-shot 3-pointer to end the half. Harrison led all UT scorers with 12 points while Kuster led the Owls, also with a dozen.
The Lady Vols scored 18 unanswered points over a span of six minutes midway through the first half to rally from down by as many as six to lead by 12 at 34-22 with 5:02 left in the half on a Graves layup.
Tennessee held Rice without a field goal for nearly nine minutes.
Tennessee rallied from down by as many as six to take the lead at 23-22 on a Cierra Burdick jumper with nine minutes left in the half.
The game started out up-tempo as Rice held a 22-16 lead with 11 minutes left in the first half. Kuster tallied 12 of the Owls' first 16.
The Lady Vols head to No. 23 Miami (Fla.) for a Sunday matchup in Coral Gables, Fla. The game can be heard on the Lady Vol Network with a 2 p.m. tipoff.