(WBIR - Knoxville) An accident this evening will shut down a portion of the interstate for several hours.

According to the Knoxville Police Department, a van and a semi-truck crashed on the 640/75 eastbound exit ramp from I-40 at 5:35 Sunday evening. The truck overturned just off the side of the exit ramp.

Both of the drivers were taken by EMS to the hospital with non-life threatening injuries.

The highway will remained closed for several hours as crews clean up the wreck.

We will give more information as it becomes available.