The Tennessee Emergency Management Agency is operating under a state of emergency as dangerous icy and snowy conditions cause significant impacts on roads and interstates around Middle and Western Tennessee.

The Tennessee Highway Patrol is asking people to stay off roadways if possible and Gov. Bill Haslam is asking people take extra precautions as the inclement weather moves across the state.

MORE: View the latest forecast here

Travel conditions in parts of the state worsened throughout the day as a wintry mix developed west-to-east, and temperatures continued to plummet.

The Tennessee Highway Patrol responds to a multi-vehicle wreck on I-40 at the 120 mile mark near Jackson on Friday, Jan. 12, 2018. Photo courtesy THP.

The Tennessee Highway Patrol responded to a wreck on Interstate 40 near mile marker 120 involving numerous tractor-trailers and passenger vehicles Friday afternoon.

In Knoxville, temperatures dropped 10 degrees in 30 minutes in the late afternoon, from 55 degrees at 4 p.m. to 45 degrees at 4:30 p.m. with a wind chill of 36 degrees.

Temperatures will continue to fall Friday night as arctic air moves into the region.

Those who must drive Friday into the evening are advised to use extreme caution due to wet, hazardous road conditions.